BRAF35 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1786-50, ES1786-100

Citations, Manuals and MSDS Available upon request.

Background: function:Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters., sequence caution:Translation N-terminally extended., similarity:Contains 1 HMG box DNA-binding domain., subcellular location:Localized to condensed chromosomes in mitosis in conjunction with BRCA2., subunit:Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein., tissue specificity:Ubiquitously expressed in adult tissues.,

Alternate Name: HMG20B; BRAF35; HMGX2; HMGXB2; SMARCE1R; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; SMARCE1-related protein; BRCA2-associated factor 35; HMG box-containing protein 20B; HMG domain-

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human HMG20B. AA range:1-50

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 36kD

Human Gene ID: 10362

Human SWISS Prot NO: Q9P0W2

Subcellular Location: Nucleus. Chromosome. Localized to condensed chromosomes in mitosis in conjunction with BRCA2.

Research Use Only