Bis-propargyl-PEG10 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1351373-48-2

Molecular Weight: 534.64

Formula: C26H46O11

Chemical Name: 4,7,10,13,16,19,22,25,28,31,34-undecaoxaheptatriaconta-1,36-diyne

Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C

InChiKey: YGYWDYNYLJLYTA-UHFFFAOYSA-N

InChi: InChI=1S/C26H46O11/c1-3-5-27-7-9-29-11-13-31-15-17-33-19-21-35-23-25-37-26-24-36-22-20-34-18-16-32-14-12-30-10-8-28-6-4-2/h1-2H,5-26H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.