IL-27A rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8732-50, ES8732-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008],

Alternate Name: Interleukin-27 subunit alpha (IL-27 subunit alpha; IL-27-A; IL27-A; p28)

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthetic peptide from human protein at AA range: 1-50

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 246778

Human SWISS Prot NO: Q8NEV9

Subcellular Location: Secreted. Does not seem to be secreted without coexpression of EBI3.

Research Use Only