Dietary Supplement Brain/Nerves Healthy Aging Metabolism Gluten Free NSF - Trusted by Sport T Exclusive NiaCel (125 mg) is NSF Certified for Sport. The body makes its energy from ATP that is produced by cell mitochondria through reactions in the citric acid (or Krebs) cycle and the electron transport chain. A key component in both processes is nicotinamide adenine dinucleotide (NAD+). That's where nicotinamide riboside (NR) comes in. Research has demonstrated that NR, the active ingredient in NiaCel, is a direct precursor to NAD+. Adequate amounts of NAD+ improves mitochondrial energetics in the heart and elsewhere and boosts production of energy-creating ATP, which provides support for endurance athletes and fatigued individuals. In addition, NR supports NAD+ as a critical substrate for the sirtuin enzymes, which play key roles in healthy aging, cognitive function, weight management, metabolic syndrome, and lipid metabolism in the liver.