MMP-11 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA27292-50, RA27292-100 Citations, Manuals and MSDS Available upon request. Background: matrix metallopeptidase 11 (MMP11) Homo sapiens Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. Alternative Names: MMP11; STMY3; Stromelysin-3; SL-3; ST3; Matrix metalloproteinase-11; MMP-11 Applications: WB; IHC-p; IF/ICC; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 4320 Protein MW (KDa): 60 SWISS: P24347 Source: Rabbit Research Use Only