TCF-3 (N601) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS2466-50, BS2466-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P15923

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play major roles in determining tissue specific cell fate during embryogenesis, like muscle or early B cell differentiation. Dimers bind DNA on E box motifs: 5' CANNTG 3'. Binds to the kappa E2 site in the kappa immunoglobulin gene enhancer.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of TCF-3 (N601) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 60 kDa

Specificity: TCF-3 (N601) polyclonal antibody detects endogenous levels of TCF-3 protein.

Alternative Name: Transcription factor E2-alpha; Class B basic helix-loop-helix protein 21; bHLHb21; Immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; Kappa-E2-binding factor; Transcription factor 3; TCF-3; Transcription factor ITF-1; TCF3; BHLHB21; E2A; ITF1

Immunogen: Synthetic peptide, corresponding to amino acids 570-620 of Human TCF-3.

Conjugate: Unconjugated

Modification: Unmodified