Me-PEG4-Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 143-24-8

Molecular Weight: 222.28

Formula: C10H22O5

Chemical Name: 2,5,8,11,14-pentaoxapentadecane

Smiles: COCCOCCOCCOCCOC

InChiKey: ZUHZGEOKBKGPSW-UHFFFAOYSA-N

InChi: InChI=1S/C10H22O5/c1-11-3-5-13-7-9-15-10-8-14-6-4-12-2/h3-10H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.