ECHA rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES16812-50, ES16812-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. [provided by RefSeq, Jul 2008],

Alternate Name: Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]

Source: Rabbit

Applications: WB

Dilution: WB 1:500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human ECHA AA range: 276-326

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 85kD

Human Gene ID: 3030

Human SWISS Prot NO: P40939

Subcellular Location: Mitochondrion. Mitochondrion inner membrane. Protein stability and association with mitochondrion inner membrane do not require HADHB.

Research Use Only