RFA1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20438-50, ES20438-100

Citations, Manuals and MSDS Available upon request.

Background: function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the replication factor A protein 1 family., subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,

Alternate Name: Replication protein A 70 kDa DNA-binding subunit (RP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding protein)

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Monkey; Mouse; Rat

Immunogen: Synthesized peptide derived from human RFA1

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 6117

Human SWISS Prot NO: P27694

Subcellular Location: Nucleus. Nucleus, PML body. Enriched in PML bodies in cells displaying alternative lengthening of their telomeres.

Research Use Only