Phospho-POLR2A (S2) Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS40518-50, BS40518-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P24928

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF, IP, FC

All Applications: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

Background: During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing.

Purification and Purity: Affinity-chromatography

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Phospho-POLR2A (S2) Antibody detects endogenous levels of total Phospho-POLR2A (S2)

Bioworld Molecular Weight: 270kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-POLR2A (S2) expression in (1) MCF7 cell lysate treated with Lambda Phosphatase; (2) MCF7 cell lysate., Immunohistochemical analysis of paraffin-embedded human spleen, using Phospho-POLR2A (S2) Antibody., Immunofluorescent analysis of MCF7 cells, using Phospho-POLR2A (S2) Antibody.

Alternative Name: POLR2A; POLR2; RNA polymerase II CTD repeat YSPTSPS;

Immunogen: A synthesized peptide derived from human POLR2A

Conjugate: Unconjugated

Modification: Phosphorylated