GGT2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES16189-50, ES16189-100

Citations, Manuals and MSDS Available upon request.

Background: GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008],

Alternate Name: Gamma-glutamyltranspeptidase 2 (GGT 2) (EC 2.3.2.2) (Gamma-glutamyltransferase 2) (Glutathione hydrolase 2) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase 2 heavy chain; Gamma-glutamyltranspeptidase 2 light chain]

Source: Rabbit

Applications: WB

Dilution: WB 1:500-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human GGT2 AA range: 89-139

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 60kD

Human SWISS Prot NO: P36268

Subcellular Location: Cytoplasm, perinuclear region. Endoplasmic reticulum. Co-localizes with calnexin in the endoplasmic reticulum.

Research Use Only