MMP9 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-93037-60, E-AB-93037-120, E-AB-93037-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: MMP9

Target Synonym: MMP9; CLG4B; GELB; MANDP2; MMP-9

Research Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Mouse, Rat

Application: IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P14780

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human MMP9

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200, IF 1:50-1:200

Calculated MW: 78kDa

Observed MW: 92KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only