Phospho-RSK2 (Ser227) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11552-50, MB11552-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P51812

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 84 kDa; Observed MW: 84 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-Rsk 2/MAPKAP Kinase 1b in C6, C6+UV lysates using Phospho-RSK2 antibody., Western blot analysis of Phospho-Rsk 2/MAPKAP Kinase 1b in 3T3, Hela lysates using Phospho-Rsk 2/MAPKAP Kinase 1b antibody.

Alternative Name: RPS6KA3; ISPK1; MAPKAPK1B; RSK2; Ribosomal protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser227 of human Rsk 2/MAPKAP Kinase 1b

Conjugate: Unconjugated

Modification: Phosphorylated