FADD Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10903-50, MB10903-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q13158

Host: Rabbit

Reactivity: Mouse,Rat

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FADD in rat Brain, 3T3Lysates using FADD antibody.

Bioworld Molecular Weight: Calculated MW: 23 kDa; Observed MW: 28 kDa

Specificity: IgG

Alternative Name: FADD; MORT1; GIG3; Protein FADD; FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity

Immunogen: A synthetic peptide of human FADD

Conjugate: Unconjugated

Modification: Unmodified