PI 3-kinase p110α rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3197-50, ES3197-100

Citations, Manuals and MSDS Available upon request.

Background: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns (4, 5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016],

Alternate Name: PIK3CA; Phosphatidylinositol 4; 5-bisphosphate 3-kinase catalytic subunit alpha isoform; PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; Phosphatidylinositol 4, 5-bisphosphate 3-kinase 110 kDa catalytic subunit

Source: Rabbit

Applications: IF; WB; IHC; ELISA

Dilution: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human PI 3-kinase p110alpha. AA range:470-519

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 110kD

Human Gene ID: 5290

Human SWISS Prot NO: P42336

Subcellular Location: intracellular, cytosol, plasma membrane, phosphatidylinositol 3-kinase complex, phosphatidylinositol 3-kinase complex, class IA, lamellipodium,

Research Use Only