DENND1B Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18656-60, E-AB-18656-120, E-AB-18656-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: DENND1B

Target Synonym: C1ORF18; C1orf218 ; Chromosome 1 open reading frame 218; Connecdenn 2; DEN1B; DENN domain containing protein 1B; DENN domain-containing protein 1B; DENN MADD domain containing 1B; DENND1B; DKFZp547O0715; FAM31B ; Family with sequence similarity 31 member B; FLJ20054; FLJ21179 ; FLJ33888; MGC103810; MGC27044; Protein FAM31B; RP11 53I24.2

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q6P3S1

Background: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.

Concentration: 0.54 mg/mL

Immunogen: Fusion protein of human DENND1B

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Calculated MW: 86 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only