HKDC1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90646-50, BS90646-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q2TB90(Human) Q91W97(Mouse)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC IHC FC

All Applications: WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Background: As the recently identified fifth isoform of hexokinase, HKDC1 catalyzes the rate-limiting and first obligatory step of glucose metabolism, which is the ATP-dependent phosphorylation of glucose to G6P. Though its particular biological function remains unclear, HKDC1 has been suggested to play a more major role in glucose metabolism during pregnancy, as the mother would need to provide enough energy for both herself and the fetus. HKDC1 is ubiquitously expressed, with the highest levels of expression in pharynx, thymus, colon, esophagus, and eye tissue.

Purification and Purity: Protein affinity purified.

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: HKDC1 polyclonal antibody detects endogenous levels of HKDC1 protein.

Bioworld Molecular Weight: 82/90/102 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining HKDC1 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining HKDC1 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: HKDC1, BC016235, Hexokinase domain containing 1, Hexokinase domain-containing protein 1, Hkdc1, HKDC1, Putative hexokinase HKDC1,

Immunogen: Recombinant protein within human HKDC1 260-460aa.

Conjugate: Unconjugated

Modification: Unmodified