RITA1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53132-60, E-AB-53132-120, E-AB-53132-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: RITA1

Target Synonym: C12orf52 ; Chromosome 12 open reading frame 52 ; RBPJ interacting and tubulin associated 1; RBPJ interacting and tubulin associated protein 1; RBPJ-interacting and tubulin-associated protein; RITA; RITA

Research Areas: Developmental biology, Neuroscience, Signal transduction, Stem cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96K30

Background: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

Concentration: 0.9 mg/mL

Immunogen: Fusion protein of human RITA1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only