[10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1446282-24-1

Molecular Weight: 358.35

Formula: C14H32O6P2

Chemical Name: [10-(diethoxyphosphoryl)decyl]phosphonic acid

Smiles: CCOP(=O)(CCCCCCCCCCP(O)(O)=O)OCC

InChiKey: QSNWJNNXAGWSQW-UHFFFAOYSA-N

InChi: InChI=1S/C14H32O6P2/c1-3-19-22(18,20-4-2)14-12-10-8-6-5-7-9-11-13-21(15,16)17/h3-14H2,1-2H3,(H2,15,16,17)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.