KMT6 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12095-50, MB12095-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q15910

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of KMT6/EZH2 in Hela, A549, HL-60Lysates using KMT6 antibody.

Bioworld Molecular Weight: Calculated MW: 85 kDa; Observed MW: 98 kDa

Specificity: IgG

Alternative Name: WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2

Immunogen: Recombinant protein of human KMT6/EZH2

Conjugate: Unconjugated

Modification: Unmodified