MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis.

Product information

CAS Number: 2271081-58-2

Molecular Weight: 390.40

Formula: C20H18N6O3

Chemical Name: 1-[(4-methoxyphenyl)methyl]-N'-[(3Z)-7-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-1H-1,2,3-triazole-4-carbohydrazide

Smiles: CC1=CC=CC2=C1NC(=O)/C/2=N\NC(=O)C1=CN(CC2C=CC(=CC=2)OC)N=N1

InChiKey: YYGUFPVMOAZQNZ-UHFFFAOYSA-N

InChi: InChI=1S/C20H18N6O3/c1-12-4-3-5-15-17(12)21-20(28)18(15)23-24-19(27)16-11-26(25-22-16)10-13-6-8-14(29-2)9-7-13/h3-9,11H,10H2,1-2H3,(H,24,27)(H,21,23,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 5 mg/mL (12.81 mM; ultrasonic and adjust pH to 2 with HCl).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.