Estrogen Receptor alpha (6F11) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3029-50, MB3029-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P03372

Host: Mouse

Reactivity: Transfected

Applications: WB

All Applications: WB: 1/500-1/1000

Background: ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Estrogen Receptor alpha in CHO-K1 and CHO-K1 transfected by Estrogen Receptor α fragmentLysates using Estrogen Receptor α antibody.

Bioworld Molecular Weight: Calculated MW: 66 kDa; Observed MW: 66 kDa

Specificity: IgG2b

Alternative Name: ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha

Immunogen: Purified recombinant human Estrogen Receptor αMMP-2 protein expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified