Parvalbumin α Polyclonal Antibody

Catalogue Numbers: BS60382-50, BS60382-100

Sizes: 50µl, 100µl

Alternative Name: Parvalbumin alpha; PVALB; Parvalbumin-α

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P20472

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Parvalbumin is a small, stable protein containing EF-hand type calcium binding sites. It is involved in calcium signaling. Typically, this protein is broken into three domains, domains AB, CD and EF, each individually containing a helix-loop-helix motif. The AB domain houses a two amino-acid deletion in the loop region, whereas domains CD and EF contain the N-terminal and C-terminal, respectively. Calcium binding proteins like parvalbumin play a role in many physiological processes, namely cell-cycle regulation, second messenger production, muscle contraction, organization of microtubules and vision. Parvalbumin expressing neurons have also been found to be in connection with various areas of clinical interest such as Alzheimer’s disease, nervous system disorders, age-related cognitive defects and some forms of cancer.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Parvalbumin α polyclonal antibody detects endogenous levels of Parvalbumin α protein.

Bioworld Molecular Weight: ~ 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Parvalbumin α polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: Mouse skeletal muscle tissue lysate
Lane 3: Rat skeletal muscle tissue lysate

Immunogen: A synthetic peptide corresponding to residues in Human Parvalbumin α.

Conjugate: Unconjugated

Modification: Unmodified