RPAP3 Polyclonal Antibody

Catalogue Numbers: BS60239-50, BS60239-100

Sizes: 50µl, 100µl

Alternative Name: RNA polymerase II-associated protein 3

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9H6T3

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. RPAP3 (RNA polymerase II-associated protein 3) is a 665 amino acid protein that contains seven TRP repeats and is expressed as multiple alternatively spliced isoforms. Existing as a tightly associated component of the RNA polymerase II (Pol II) complex, RPAP3 functions to form an interface between Pol II and scaffolding proteins, thereby playing a role in the regulation of protein complex formation.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RPAP3 polyclonal antibody detects endogenous levels of RPAP3 protein.

Bioworld Molecular Weight: ~ 76 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of RPAP3 polyclonal antibody at 1:500 dilution
Lane 1: Jurkat whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: Mouse kidney tissue lysate

Immunogen: A synthetic peptide corresponding to residues in Human RPAP3.

Conjugate: Unconjugated

Modification: Unmodified