AR-α2C (R369) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS1945-50, BS1945-100

Sizes: 50µl, 100µl

Swiss-Prot: P18825

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

Background: Alpha-2C adrenergic receptors (α2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. α2C-AR can influence Parkinson’s disease, panic disorders, and Huntington disease (HD) progression. α2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: AR α2C (R369) polyclonal antibody detects endogenous levels of AR α2C protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of AR-α2C (R369) pAb at 1:500 dilution
Lane 1: A549 whole cell lysate (40ug)
Lane 2: U-87MG whole cell lysate (40ug)
Lane 3: H9C2 whole cell lysate (40ug)
Lane 4: CT26 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of AR-α2C (R369) pAb pAb in paraffin-embedded human kidney carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Bioworld Molecular Weight: ~ 70 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Alpha-2C adrenergic receptor; Alpha-2 adrenergic receptor subtype C4; Alpha-2C adrenoreceptor; Alpha-2C adrenoceptor; Alpha-2CAR; ADRA2C; ADRA2L2; ADRA2RL2; α-2C adrenergic receptor; α-2 adrenergic receptor subtype C4; α-2C adrenoreceptor; α-2C adrenoceptor; α-2CAR; ARα-2C; AR α2C; ARα2C; ARα 2C;

Immunogen: Synthetic peptide, corresponding to amino acids 340-390 of Human AR-α2C.

Conjugate: Unconjugated

Modification: Unmodified