BACE Monoclonal Antibody Size: 50μL, 100μL Catalogue Numbers: RA10827-50, RA10827-100 Citations, Manuals and MSDS Available upon request. Background: beta-secretase 1 (BACE1) Homo sapiens This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015], Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol. Storage Instructions: -20°C/1 year Applications: WB Species Cross-Reactivity: Human; Rat; Bovine; Dog; Pig GeneID (Human): 23621 SWISS: P56817 Source: Mouse Research Use Only