TSHZ3 Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS77760-50, BS77760-100 Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: Q63HK5 Host: Rabbit Reactivity: Human, Mouse Applications: WB All Applications: WB,1:500 - 1:2000 Background: This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients. [provided by RefSeq, Jul 2016] Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity: Unmodification Extra Notes: Western blot analysis of extracts of various cell lines, using TSHZ3 Rabbit pAb at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s. Note: For research use only, not for use in diagnostic procedure. Bioworld Molecular Weight: 119kDa Alternative Name: TSH3; ZNF537; TSHZ3 Immunogen: Recombinant fusion protein of human TSHZ3(NP_065907.2). Conjugate: Unconjugated Modification: Unmodified