PERK Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA10635-50, RA10635-100

Citations, Manuals and MSDS Available upon request.

Background: eukaryotic translation initiation factor 2 alpha kinase 3 (EIF2AK3) Homo sapiens The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 9451

SWISS: Q9NZJ5

Source: Mouse

Research Use Only