BCL2L12 Polyclonal Antibody

Catalogue Numbers: BS67646-50, BS67646-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q9HB09

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of BCL2L12 protein.

Extra Notes: Western blot analysis of BCL2L12 expression in K562 (A), HEK293T (B) whole cell lysates.

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: BPR; Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L12. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified