Dnmt1 Polyclonal Antibody

Product: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Sizes: 50µl, 100µl

Catalogue Numbers: BZ17024-50, BZ17024-100

Swiss-Prot: P26358

Host: Rabbit

Reactivity: Human

Applications: FC,WB

All Applications: WB: 1/500-1/1000 FC: 1/50-1/100

Background: Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Calculated MW: 183 kDa; Observed MW: 183 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of DNMT1 in Jurkat lysates using Dnmt1 antibody.

Alternative Name: ADCADN; CXXC finger protein 9; CXXC9; DNA methyltransferase 1; DNA MTase; Dnmt1o; HSN1E; M.HsaI; MCMT; Met1; MommeD2

Immunogen: A synthetic peptide of human Dnmt1

Conjugate: Unconjugated

Modification: Unmodified