MYBPC2 Polyclonal Antibody

Catalogue Numbers: BS60182-50, BS60182-100

Sizes: 50µl, 100µl

Alternative Name: Myosin-binding protein C, fast-type; Fast MyBP-C; C-protein, skeletal muscle fast isoform; MYBPC2; MYBPCF

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q14324

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: MYBPC2, also known as MYBPCF or MYBPC, is a 1,142 amino acid protein that contains 3 fibronectin type-III domains and 7 Ig-like C 2-type domains. Existing as a member of the immunoglobulin superfamily, MYBPC2 functions as a thick filament-associated protein that localizes to striated muscle bands in vertebrae and is thought to modify the activity of select ATPases. Additionally, MYBPC2 may play a role in the modulation of muscle contraction and in the overall structural integrity of the cell. The gene encoding MYBPC2 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MYBPC2 polyclonal antibody detects endogenous levels of MYBPC2 protein.

Bioworld Molecular Weight: ~ 128 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of MYBPC2 polyclonal antibody at 1:500 dilution
Lane 1: Hela whole cell lysate
Lane 2: NIH-3T3 whole cell lysate
Lane 3: H9C2 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human MYBPC2.

Conjugate: Unconjugated

Modification: Unmodified