M-CSF Receptor Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11197-50, MB11197-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P09581

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of M-CSF Receptor in K562Lysates using M-CSF Receptor antibody.

Bioworld Molecular Weight: Calculated MW: 109 kDa; Observed MW: 109 kDa

Specificity: IgG

Alternative Name: M-CSF Receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115

Immunogen: Recombinant protein of mouse MCSF Receptor

Conjugate: Unconjugated

Modification: Unmodified