NAIP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8810-50, ES8810-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by Ref

Alternate Name: Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000

Reactivity: Human; Mouse

Immunogen: Synthetic peptide from human protein at AA range: 1191-1240

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 4671

Human SWISS Prot NO: Q13075

Subcellular Location: cytoplasm, basolateral plasma membrane, neuron projection, perikaryon, extracellular exosome,

Research Use Only