Azido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 356046-26-9

Molecular Weight: 332.36

Formula: C12H24N6O5

Chemical Name: 1,17-diazido-3,6,9,12,15-pentaoxaheptadecane

Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCN=[N+]=[N-]

InChiKey: OQHIMLOZSDFRID-UHFFFAOYSA-N

InChi: InChI=1S/C12H24N6O5/c13-17-15-1-3-19-5-7-21-9-11-23-12-10-22-8-6-20-4-2-16-18-14/h1-12H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.