MRPS18B Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-52720-60, E-AB-52720-120, E-AB-52720-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: MRPS18B

Target Synonym: 28S ribosomal protein S18-2; 28S ribosomal protein S18b; 28S ribosomal protein S18b; mitochondrial; C6orf14; DKFZp564H0223; HSPC 183; HSPC183; mitochondrial; Mitochondrial ribosomal protein S18 2; Mitochondrial ribosomal protein S18B; MRP S18 2; MRP S18 b; MRP S18b; MRP-S18-2; MRP-S18-b; MRPS 18B; MRPS18 2; Mrps18-b; MRPS18B; PTD017; RT18B; S18amt; S18mt-b

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9Y676

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.

Concentration: 0.6 mg/mL

Immunogen: Fusion protein of human MRPS18B

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Calculated MW: 29 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only