Bromo-PEG3-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 220568-33-2

Molecular Weight: 297.19

Formula: C11H21BrO4

Chemical Name: 2-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}oxane

Smiles: BrCCOCCOCCOC1CCCCO1

InChiKey: NMSUTJVEBXQTQM-UHFFFAOYSA-N

InChi: InChI=1S/C11H21BrO4/c12-4-6-13-7-8-14-9-10-16-11-3-1-2-5-15-11/h11H,1-10H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.