IHH Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB67101-50, MB67101-100

Product: Mouse IgG3. Supplied in crude ascites with 0.01% sodium azide.

Swiss-Prot: Q14623

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/4000)

Background: Indian hedgehog (Ihh) is a cell signaling protein that is one of the three proteins in the hedgehog family. Ihh is expressed in adult kidney and liver and acts as an antagonist of the Wnt signaling pathway in colon cancers. The Wnt signaling pathway plays a role in carcinogenesis and in embryonic development, and any gene mutations in this pathway lead to various diseases. The Ihh protein is involved in chondrocyte differentiation, proliferation, and maturation especially during endochondral ossification, and is a regulator of bone growth.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of IHH protein.

Bioworld Molecular Weight: ~ 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of IHH expression in CEM (A) whole cell lysates., ???, ???, ???

Indian hedgehog protein; IHH; HHG-2

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human IHH. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified