EAAT2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20771-50, ES20771-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010],

Alternate Name: Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2)

Source: Rabbit

Applications: WB

Dilution: WB 1:1000-2000

Reactivity: Human; Rat; Mouse

Immunogen: Synthetic Peptide of EAAT2 AA range: 370-420

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 62kD

Human Gene ID: 6506

Human SWISS Prot NO: P43004

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only