Cav2.2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20796-50, ES20796-100

Citations, Manuals and MSDS Available upon request.

Background: calcium voltage-gated channel subunit alpha1 B (CACNA1B) Homo sapiens The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

Alternate Name: Voltage-dependent N-type calcium channel subunit alpha-1B (Brain calcium channel III; BIII; Calcium channel, L type, alpha-1 polypeptide isoform 5; Voltage-gated calcium channel subunit alpha Cav2.2)

Source: Rabbit

Applications: IHC; IF

Dilution: IHC 1:50-100

Reactivity: Human; Rat; Mouse

Immunogen: Synthetic Peptide of Cav2.2 AA range: 230-310

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 263kD

Human Gene ID: 774

Human SWISS Prot NO: Q00975

Subcellular Location: Membrane; Multi-pass membrane protein.

Research Use Only