HNP-1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB9273-50, MB9273-100

Product: Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P59665(Human)

Host: Mouse

Reactivity: Human, Rat

Applications: WB, IHC

All Applications: WB:1:500-1:2,000
IHC:1:50-1:200

Background: Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Purification and Purity: ProG affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: HNP-1 monoclonal antibody detects endogenous levels of HNP-1 protein.

Bioworld Molecular Weight: 10 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of HNP-1 on rat spleen tissue lysates using anti-HNP-1 antibody at 1/500 dilution., Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-HNP-1 antibody. Counter stained with hematoxylin.

Alternative Name: HP-1, HP1, HP-2, HP2, DEFA1, DEF1, DEFA2, MRS, alpha 1, DEF1, DEF1, DEFA1, DEFA1B, DEFA2, Defensin 1, Defensin, Defensin, alpha 1, Defensin, alpha 1, myeloid related sequence, Defensin, alpha 2, HNP-1, HNP-2, HNP1, HP-1, HP-2, HP1, HP2, MRS, Myeloid related sequence, Neutrophil defensin 1, Neutrophil defensin 2,

Immunogen: Peptide

Conjugate: Unconjugated

Modification: Unmodified