The tissue transglutaminase IgA (tTg-IgA) test is a vital tool in diagnosing celiac disease, an autoimmune condition where the body mistakenly attacks the enzyme tissue transglutaminase (tTG) when exposed to gluten in wheat, barley, rye, and oats. By detecting antibodies produced by the immune system, this blood test helps identify elevated levels of antibodies indicative of celiac disease. Celiac disease, a chronic autoimmune disorder, leads to small intestine damage upon gluten consumption, causing symptoms like bloating, diarrhea, and abdominal pain. Factors contributing to its development include genetic predisposition, early childhood gluten exposure, certain infections, and other autoimmune conditions like type 1 diabetes and thyroid disease. Symptoms vary but may include digestive issues, skin rashes, dental problems, growth delays, and mood changes, emphasizing the importance of timely diagnosis and management to prevent long-term complications and nutrient deficiencies.

Turnaround:2 days

Sample Type:: Blood

Please post self-collected samples on the same day they are taken, avoid posting over weekends and bank holidays. ** If Tissue Transglutaminase (TAA) is regulated and is LOW (<0.2U/ml) total IgA will be reflexed. If total IgA is low (<0.1g/L) deamidated gliadin IgG will be reflexed. If Tissue Transglutaminase (TAA) is HIGH (>10 U/ml), endomysial IgA will be reflexed as confirmatory test for first time positive samples.

Download Kit instruction