AFP Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-13768-60, E-AB-13768-120, E-AB-13768-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: AFP

Target Synonym: Afp; AFPD; Alpha fetoglobulin; Alpha fetoprotein; Alpha fetoprotein precursor; Alpha-1-fetoprotein; Alpha-fetoglobulin; Alpha-fetoprotein; alpha-fetoprotein; Hereditary persistence of; included; FETA; FETA; Hereditary persistence of alpha fetoprotein; HPAFP

Research Areas: Cancer, Cardiovascular, Developmental Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P02771

Background: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Concentration: 0.5 mg/mL

Immunogen: Recombinant protein of human AFP

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Calculated MW: 69kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only